You could check out
NoScript, I used to use it long ago before I switched to uBlock Origin but it (uBO) now struggles on some sites or is completely ineffective. Some pages need to be reloaded (after first loading from clicked link) to block ads.
I recall now, there is some change in Chrome browser engine that was expected to put some or all adblockers out of business. maybe that is now happening.
NoScript is rather radical and it might work where other blockers fail. It is just a bit pain the way you need to allow this or that to get web pages to function. It used to have more relaxed option where top level domain names would be allowed to some extent and then you could set more strict filtering as needed.
In uBlock Origin, if you select to block something via Pick, it seems it can only block one picked item, if you pick another one, the first is unblocked.
I may have to switch to browsers that offer so called 'reading' option, where it cancels all graphics, media.